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Larson AN, Ledonio CG, Brearley AM, Sucato DJ, Carreon LY, Crawford AH, et al

The number of osteoclasts within the femoral condyle was quantified using Tartrate-resistant acid phosphatase (TRAP) staining, performed in accordance with previously reported methods [32]

Metalloproteinase 3 (MMP3), MMP10, and MMP12 degrade the recombinant factor VIII, resulting in protein heterogeneity, denaturation, and attenuation of protein function 8

The proposed mechanism for the cause of favism is that these new compounds then undergo redox cycling and in the process deplete reduced glutathione, leading to the formation of free radicals and hydrogen peroxide that damage red blood cells in individuals deficient in G6PD